The role of messenger RNA in DNA repair
Science

The role of messenger RNA in DNA repair

When it breaks, it must be repaired correctly. Sometimes an RNA molecule gets trapped in the vicinity of a DNA break and must be removed for faithful
DNA damage in tissue-infiltrating macrophages triggers an exosome-based metabolic reprogram
Science

DNA damage in tissue-infiltrating macrophages triggers an exosome-based metabolic reprogram

A strategy to deliver ribonuclease H nucleases in inflammatory Ercc1/ pancreatic cells. The treatment of Ercc1/ animals with the EV-delivered
The Gene-Synthesis Revolution
Science

The Gene-Synthesis Revolution

A decade ago, when Emily was a director of research at the life-sciences giant, a pair of scientist-engineers in their 50s came to her with an idea
DNA replication under the microscope
Science

DNA replication under the microscope

Scientists at KAUST use electron microscopes to investigate the function and structure of key protein complexes. Credit: Heno Hwang. Cryo-EM has
Novel artificial genomic DNA can replicate and evolve outside the cell: Hopes for the construction of artificial cells that can grow and evolve autonomously
Science

Novel artificial genomic DNA can replicate and evolve outside the cell: Hopes for the construction of artificial cells that can grow and evolve autonomously

Professor Norikazu Ichihashi and his colleagues at the University of Tokyo have succeeded in inducing gene expression from a DNA, characteristic of