Lift, a $699.99 wireless vertical mouse, is launching today in multiple colors, as well as with both right- and left-handed options. The Lift has a design that puts your hand at a 57 degree angle for better ergonomics. Since you're holding your wrist at a similar angle to shaking someone's hand, using mice like the Lift may help to reduce wrist strain. That was what I experienced. I switched to a split keyboard and a Lift mouse last year.
If you don't want to spend a lot of money, the Lift could be a good starting point. It doesn't have a charging port, instead relying on a single AA battery that can last up to two years.
The Lift ditches the elegant design of the MX Vertical for something that is more simplified and playful, and you can get it in pink, silver, or graphite. The rubber grip keeps it snug in your palm, and most of the same functions are here. The mouse has two main buttons, a scroll wheel and a switch. There is a button on the bottom of the Lift that you can use toggling between three devices that you can connect to the Lift.
The mouse supports the unique software feature that allows the mouse to be used on multiple computers even if they run a different OS. The Logi Options Plus app will need to be running on both computers. The app can be used to copy and paste files. I've seen a hands-on demo of the software, but it wouldn't work with me at home.
The Lift is included with the new Bolt receiver that can connect to a PC with a port for the internet. This one has better security than the previous one. You can use its function without using a receiver.
The transition from a standard mouse to the Lift has gone better than I anticipated. The learning curve isn't too bad since this mouse has a similar button layout to mice that I'm accustomed to using. The Lift is a good option to start with since it costs under $100.