Vitamin K2 repairs nerve cells via mitochondrial quality control loop
Schematic illustration of the protective role of vitamin K2 in 6-OHDA-induced cytotoxicity in SH-SY5Y cells. Credit: Tang Hengfang

A research group led by Prof. Zheng Zhiming from the Hefei Institute of Physical Science (HFIPS) of the Chinese Academy of Sciences has found a novel function of vitamins K2 and C.

The mechanism of the anti-oxidant function of vitamin K2 is not fully understood. The nerve agent can cause damage to dopamine neurons, which can lead to death. Parkinson's and other neurodegenerative diseases are often caused by it.

Scientists found that vitamins K2 and K3 can protect nerve cell damage.

B-cell lymphoma-2 is one of the oncogenes that plays a role in the main switch of apoptosis by upregulating the expression.

It maintains the normal operation of the Mitochondrial fusion, division, autophagy and generation so as to control the normal operation of the Mitochondrial quality control loop.

The results show that the prevention and treatment of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease can be done by repairing nerve cell damage.

More information: Hengfang Tang et al, Vitamin K2 Modulates Mitochondrial Dysfunction Induced by 6-Hydroxydopamine in SH-SY5Y Cells via Mitochondrial Quality-Control Loop, Nutrients (2022). DOI: 10.3390/nu14071504 Citation: Vitamin K2 repairs nerve cells via mitochondrial quality control loop (2022, April 14) retrieved 14 April 2022 from https://phys.org/news/2022-04-vitamin-k2-nerve-cells-mitochondrial.html This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.