The power of a plant-based diet is preached by Deanna Minich. The vast majority of Americans don't eat the recommended amount of fruits and vegetables, so much so that much of her research as a nutrition scientist at the University of Western States revolves around that.

Minich has encountered questions from both academics and lay audiences about anti-nutrients, compounds found in plants that can meddle with the absorption of nutrients into the bloodstream.

Anti-nutrients evolved to protect flora from threats like insects andbacteria, which may not sound particularly helpful to us humans.

Minich wanted to provide a satisfying answer on the health impacts of anti-nutrients. Although scientists have spent decades digging into these impacts, the existing evidence doesn't necessarily offer clear conclusions, but still suggests that anti-nutrients can influence our bodies in a variety of fascinating, complex ways.

Should We Be Wary of Anti-Nutrients?

Fruits, vegetables, whole grains and legumes are some of the plant foods that people commonly eat. They can prevent people from taking important substances. It may be surprising to learn that even a vegetarian diet could potentially spur adverse outcomes.

How worried should we be? Research hasn't yet shown how much people lose from food due to anti-nutrients. Studies have identified safe thresholds for certain anti-nutrients, and most people don't exceed them when food is properly prepared, says a food science PhD candidate at Francisco.

It is important to note that the concentrations of anti-nutrients in foods can be unpredictable. The levels of certain compounds have been found to vary between different varieties of soy. It is clear that not every stir fry will have the same effect.

Many of the concerns associated with anti-nutrients may affect people with underlying conditions. Individuals who don't consume enough iodine may be affected by goitrogens in foods like cabbage and brussels sprout. It is difficult to set a threshold for everyone because each individual is unique.

Oxalates in items such as tea, green leafy vegetables, nuts and beets can prevent the absorption of certain vitamins and minerals. People with calcium deficiencies may be at higher risk of developing kidney stones because oxalates stick to calcium. For most people, oxalate-rich foods like spinach can reduce the risk of stone formation.

Those with certain mineral deficiencies, such as the type of anemia that is associated with low iron levels, should also pay attention to anti-nutrients. The absorption of important minerals can be impaired by the presence of phytates in foods like nuts, grains and legumes. Tea decreased iron absorption by 37 percent when consumed with a meal, but waiting an hour after eating reduced this effect.

Beans, cabbage, broccoli and asparagus have anti-nutrients that can cause burping, stomach discomfort and flatulence.

Dietary Diversity and Cooking Methods Matter

It's important to eat a wide variety of vegetables to avoid taking in high amounts of one specific anti-nutrient, and mixing certain foods can help to minimize impacts because plant ingredients can work synergistically. Foods rich in fiber and vitamins C can help us absorb vitamins and minerals from plants.

Meal preparation is important. Despite a lack of solid evidence in humans, some researchers argue that lectins in chickpeas and other chickpeas may cause damage to the gut, promote the growth of harmfulbacteria, and contribute to celiac disease.

The concentration of lectins in a meal can be reduced by cooking, germination and fermentation. The method of boiling may reduce the form of oxalates up to 87 percent. After a few minutes of boiling broccoli, glucosinolates can shrink in half.

Smoothie fans may wonder if daily concoctions with lots of raw greens are a good idea. Minich says this depends on the individual and how much they are consuming. If you are sensitive to oxalates or goitrogens, you should avoid or minimize portions of these foods. According to a report by the European Food Safety, green smoothies sold in German stores were found to exceed a safe value of oxalic acid with just a single portion.

When people can plan a diverse diet, anti-nutrients are important. Researchers have pointed out how processing methods like fermentation are crucial to reduce anti-nutrient contents when these foods are consumed in abundance. Preserving the anti-nutrient effects of food and beverages has been done for thousands of years.

It's easy to assume that vegetarians would be more vulnerable to the effects of anti-nutrients, but some studies suggest that they may be able to increase their absorption of zinc and iron.

Minich says a diverse diet rich in plants has benefits for most people that outweigh the potential negatives. Reducing anxiety and a more diverse gut microbiome are some of the advantages associated with mixing up your meals.

Many of the ill effects of anti-nutrients have been observed when studying isolated compounds in animal models, which doesn't reflect a balanced diet in people. Studies that look into the effects of the whole foods they're found in don't always offer clear conclusions. There are some observational and epidemiological studies on the subject.

Flipping the Script 

It may sound odd, but labs are looking into the possibility of isolating and wielding anti-nutrients for their effects against diseases like cancer, asthma, diabetes and Alzheimer's. The majority of this work has been done in animals and cells. There is a need to standardize therapeutic doses, conditions and population groups that could benefit from supplementation with one of these compounds, according to a scientist from Spain.

Some studies claim to find benefits from consuming anti-nutrients in meals. The risk of cardiovascular diseases in post-menopausal women can be reduced by the use of soy beans, tofu, sesame seeds and other fares. Lectins in the diet can reduce the risk of developing heart conditions and type 2 diabetes. Researchers often claim that tannins and other polyphenols can help protect against a variety of conditions.

Anti-nutrients may experience an epic redemption similar to that of dietary fiber, as noted by public health nutrition researcherJill Joyce in The Conversation. In the late 19th century, people thought fiber was bad for us and that it was removed from cereals and flours. Fiber can lower cholesterol and blood pressure, among other benefits. More research will shed more light on how anti-nutrients can affect human health.