Alexander paid tribute to his TV mama, who died at age 93.
The stage and screen actor, who starred as George Costanza's high-pitched, high-drama mother on the sitcom, passed away on Saturday in Palm Desert, California, her agent confirmed.
Harris and Jerry Stiller starred as George's parents, Frank and Estelle, who were constantly throwing barbs at each other and giving advice to their son. The 1992 Emmy Award-winning Seinfeld episode, "The Contest", featured Estelle.
Alexander said that his tv mama, Estelle Harris, passed away.
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Frank Costanza originally roared "Serenity now!", a phrase taken from his relaxation cassette, but Alexander used it in a moving moment for fans.
I adore you, Estelle. He wrote that he loved your family.
"Serenity now and always." Credit: NBCU Photo Bank / NBCUniversal via Getty Images via Getty Images
Julia Louis Dreyfus plays Elaine Benes on the show.
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Harris was born in New York City on April 22, 1928 and grew up in Pittsburgh. She played Mrs. Potato Head in the Toy Story franchise, bringing the same kind of chaotic energy to the role.