The first person to receive a heart transplant from a pig has died two months later. David Bennett died at the University of Maryland Medical Center. Doctors didn't give an exact cause of death, but they said his condition had begun to get worse. Bennett's son praised the hospital for offering the last-ditch experiment, saying the family hoped it would help end the organ shortage. David Bennett Jr. said in a statement released by the University of Maryland School of Medicine that they are grateful for every innovative moment, every crazy dream, and sleepless night that went into this historic effort. Doctors want to use animal organs for transplants one day. Bennett, a handyman from Hagerstown, Maryland, was a candidate for this newest attempt only because he was ineligible for a human heart transplant, bedridden and on life support, and out of other options. Bennett's son told The Associated Press that his father knew there was no guarantee it would work. Prior attempts to transplant an animal's organs have failed because patients quickly reject the animal's organs. The Maryland surgeons used a pig heart that had been altered to remove pig genes that cause hyper-fast rejection and add human genes to help the body accept the organ. Bennett seemed to be slowly recovering after the pig heart was functioning at first. The hospital released video of him watching the Super Bowl from his hospital bed while working with his physical therapist. Bennett survived longer with the pig heart than Baby Fae did with a baboon's heart in 1984. We are devastated by the loss of Mr. Bennett. He was a brave and noble patient who fought all the way to the end, according to the doctor who performed the surgery. There is a need for another source of organs. A record number of transplants were performed in the US last year. Thousands of people die every year before getting an organ, and thousands more never get added to the national waiting list, considered too much of a long shot. The dramatic Maryland experiment was allowed by the Food and Drug Administration. Bennett's doctors said he had heart failure and an irregular heartbeat, as well as a history of not complying with medical instructions. He wasn't eligible for a human heart transplant that required strict use of immune-suppressing medicines or an implanted heart pump. Bennett's death was not revealed by doctors. There are risks for transplant recipients. The scientific director of the Maryland university said they have gained valuable insights from Bennett's experience that the pig heart can function well within the human body. One next question is whether scientists have learned enough from Bennett's experience and some other recent experiments with gene-edited pig organs to persuade the FDA to allow a clinical trial. Twice last fall, surgeons at New York University got permission from the families of deceased individuals to temporarily attach a pig kidneys to blood vessels outside the body and watch it work before ending life support. The surgeons at the University of Alabama at Birmingham are trying to get a pair of pig kidneys into a brain-dead man in a step-by-step rehearsal for an operation they hope to try later this year. Pig heart valves and pig skin have been used in human medicine. It is more complex to transplant entire organs than it is to use highly processed tissue. The pigs used in these experiments were provided by Revivicor, a subsidiary of United Therapeutics, which is one of several companies trying to develop pig organs for potential human transplant. There is a The Howard Hughes Medical Institute supports the Associated Press Health and Science Department. The AP does not accept responsibility for the content. There are latest Indiana COVID-19 statistics. 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