England v Wales: Harry Randall will start for hosts at scrum-half, Courtney Lawes captains

The captain for the Six Nations match between England and Wales will beCourtney Lawes, with Harry Randall starting at scrum-half.

Ben Youngs will have to wait to win a record 115th cap from the bench as he is Randall's replacement for the second game.

Tuilagi is back in the middle with Henry Slade.

Alex Dombrandt starts at number eight, with Sam Simmonds on the bench.

The England team to face Wales are: Smith, Randall, Genge, Sinckler, Ewels, Itoje, Curry, Dombrandt.

George, Marler, Stuart, Isiekwe, Simmonds, Youngs and Ford are replacements.

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In the front row, prop Kyle Sinckler pushes Will Stuart to the bench to make his 50th England appearance, while hooker Luke Cowan-Dickie starts in place of Jamie George.

Lawes has not played since mid-January because of a concussion, but has been declared fit to start and regain the captaincy he had against South Africa in the autumn, with flanker Tom Curry standing down from the role.

It is the first time in history that the captains of England and Wales have both come from the same club.

Youngs is set to surpass the record of 114 caps held by Leonard if he takes to the field.

England lost their opening game against Scotland and need a victory against Wales to keep their title hopes alive.

Wales won one and lost one of their games so far, despite recalling wing Josh Adams and number eight Taulupe Faletau for the game.

Jones praises 'young, hungry squad'

Randall and Marcus Smith played a part in the attack against Italy in Rome.

Eddie Jones praised his youthful players, but the Welsh side will provide a tougher Test for the pair.

Jones said that the squad had trained with real intensity this week.

It will be an exciting Test match in front of a full crowd when Wales take on England at Twickenham.

We can't wait to play in front of our supporters again and we are ready to go at them.

It will be a special match with two significant milestones for Ben and Kyle, both of whom have made outstanding contributions to English rugby so far in their careers. We know there is more to come for them.