Psilocybin Has No Short- Or Long-Term Detrimental Effects In Healthy People

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BeauHD posted on Tuesday January 4, 2022.

The Institute of Psychiatry, Psychology, and Neuroscience (IoPPN) at King's College London has found that it is possible to give up to six participants a single dose of 10 or 25mg of psilocybin. The research published in The Journal of Psychopharmacology is an essential first step in demonstrating the safety and feasibility of using the drug in controlled settings. Current treatment options for these conditions are not effective for many people. There has been early research that suggests a potential for a therapy to treat these groups, but no trials have been done at the scale needed for regulatory approval.

The trial is the first of its kind to investigate the simultaneous administration of drugs. 89 healthy participants with no recent use of the drug were recruited. 60 people were randomly picked to receive a dose of the drug in a controlled environment. All participants received one-to-one support from trained therapists. The control group of 29 people received a placebo and acted as if they were in control. The participants were closely monitored for six to eight hours after the administration of the drug. They were assessed for a number of possible changes, including their ability to process emotions, as well as their ability to plan. There were no instances of anyone withdrawing from the study due to an adverse event, and there were no trends to suggest that either of the doses had any long-term detrimental effects on participants.

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