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Billions of dollars of losses have been caused by the Pandemic.
There have been more Covid-related flight cancelations as the week starts, capping off a miserable festive period for thousands of people.
The FlightAware data tracking website says Chinese and US destinations were the worst hit on Monday, with more than 1,300 flights canceled.
US airlines say crews testing positive are to blame for the disruption.
Hong Kong is banning all Korean Air flights for two weeks after some positive cases.
Over the long Christmas weekend, more than 8,000 flights have been grounded.
The number of cancellation is higher than normal at a time of year when people travel to spend time with their loved ones.
Billions of dollars of losses for airlines have been caused by the Pandemic, so they hope the disruption ends soon.
Several of the cruise ships that were hit by Covid cases were denied port in the Caribbean, with US authorities monitoring dozens of them.
The Omicron variant is driving the rising Covid cases around the world.
China Eastern and Air China were the two Chinese companies that had the majority of the flights canceled on Monday.
The worst affected airports are Beijing and Shanghai. The Chinese authorities have not commented on the issue.
The airport in the northern Chinese city of Xi'an is on the list. More than 13 million people in the city have been ordered to stay indoors as authorities try to contain a Covid outbreak.
The worst hit US companies are United and JetBlue.
The spike in Omicron cases had a direct impact on our flight crews and the people who run our operation, with many employees required to self-isolate after coming into contact with those that were Omicron. Omicron is the dominant strain in the US.
Severe weather is a factor. A blanket of snow in the western state of Washington caused travel chaos on Sunday.
British Airways has 42 cancelations on Monday in the UK. There are 46 scrapped flights at London's Heathrow airport.
According to the University of America, over five million people have died from coronaviruses. There have been over 260 million confirmed cases.
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"An event is better than a life is canceled", said Dr. Tedros Adhanom Ghebreyesus.
