Richarlison tore his calf in the loss to Crystal Palace.
Richarlison will be out for a number of weeks with a calf injury.
He was taken out of the game after 58 minutes, and booed by the fans.
He said after the game that he had taken him off because of the injury.
The Palace match resulted in a fractured foot and bone damage for captain Seamus Coleman.
The top football tweet is 'Worst substitution ever' or 'Rafa genius'.
Both players will continue to be assessed.
Dominic Calvert-Lewin has been out since August with a thigh problem.
Midfielder Tom Davies and defender Yerry Mina were both out for two months with knee and calf injuries, but were both able to return.
The team is currently 14th in the league.
The mistakes cost the club.
Following a meeting on Monday, the club will continue to discuss how supporters can be represented at board level, as they are committed to creating a fan advisory board.
The club met representatives from the ESDG to discuss how it can better involve fans in strategic matters after a 10,000-strong survey earlier in the season.
