Manchester United knocked out Paris Saint-Germain in the last 16 of the European Championship in 2019.
Paris St-Germain will face Manchester United in the last 16 of the competition.
Two of the greatest players of all time are in the same tie.
Six-time winners Red Bull Salzburg will face off against six-time winnersLiverpool.
Manchester City will play last season's Europa League winners.
Last season's final was the first time that the side had ever won the competition.
The draw appeared to have been made in error when United were drawn against the same team as they were in the same group.
The first and second legs will be on February and March.
The other three English teams are all away in the first leg, with the only one playing at home.
The away goals rule has been removed so ties will go to extra time after 180 minutes.
If the teams can't be separated after 30 minutes, it goes to a penalty shootout.
The season's final will take place in St Petersburg, Russia.
The draw for the last-16 of the competition.
Real Madrid vs. Benfica.
Manchester City vs.
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Red Bull Salzburg is playing
Inter Milan is playing a game.
The game is between Sporting Lisbon and Juventus.
The game is between Lille and Chelsea.
Manchester United vs. Paris Saint-Germain.
A meeting of two greats.
The chief football writer is Phil McNulty.
The draw for the last-16 of the European Championship left Manchester United with Paris St-Germain and set up a meeting between the two greatest players of all time.
The five-time winner of the competition has inspired progress into the last 16 while the Ballon d'Or winner Messi wants to help his new club win the title for the first time.
The manager many believe may well be at Old United next season, Mauricio Pochettino, will lead the team in a game that is short on narratives.
It is a tough draw for United's interim boss, but not without hope, as he has to work out a way to stop Kylian Mbappe and Neymar, despite the fact that Messi is the best player in the world.
It will bring back memories of United's amazing comeback against Paris in the first leg of the European Championship in March, when they overcame a 2-0 first-leg deficit to reach the quarter-finals.
There will be a sense of cautious optimism for the other clubs, as life could have been much harder, with the exception of Red Bull Salzburg.
Manchester City will be quietly confident of progressing against Villarreal, but managerPep Guardiola will be wary of Unai Emery's team, who won the Europa League last season.
