Stocks making the biggest moves premarket: American Airlines, AutoZone, GlaxoSmithKline and others

Check out the companies that are making news.

Doug Parker will step down as CEO of American Airlines on March 31 and remain as chairman. He will be replaced as CEO by Robert Isom. The American rose in the premarket.

The auto parts retailer reported a quarterly profit of $25.69 per share, beating the consensus estimate of $20.87. Comparable store sales jumped 13.6%. StreetAccount had predicted a 5% rise in comp-store sales.

The footwear retailer beat estimates by 30 cents with adjusted quarterly earnings of 86 cents per share, but revenue fell short of Wall Street forecasts. The surge in comparable store sales was less than the analysts had anticipated. In premarket trading, shares rallied 3.7%.

Glaxo said early-stage studies showed that its Covid-19 therapy is effective against the omicron variant. Glaxo added 0.6% in premarket trading.

According to internal documents seen by CNBC, the company is replacing faulty cameras on some of its models. A driver can see a blank or choppy video on a car's primary display if the cameras are on. In a report issued by the Swiss bank, it said that no rival would be close to the electric car maker in the years to come. The company gained 3.5% in premarket action.

According to a Wall Street Journal report, the company that makes Corona beer agreed to build a new brewery in southeastern Mexico. Two years after the government forced the closing of a nearly completed plant near the U.S.-Mexican border, an agreement is set to be announced.

The business software company earned an adjusted 31 cents per share for its latest quarter, well above the 2-cent consensus estimate, with revenue also topping forecasts. Its loss widened from a year ago with a surge in operating expenses, and shares plummeted in premarket trading.

The private equity firm Permira will acquire Mimecast for about $5.8 billion in cash. Mimecast was up in the premarket.

After the database platform company reported a smaller-than-expected quarterly loss and beat Street revenue forecasts, it surged 20.3% in premarket action. Increased demand from businesses for online connections has led to a raised financial outlook for MongoDB.

The chip maker's shares surged 8.8% in premarket trading after it said it would take its Mobileye self-driving car unit public. The Wall Street Journal reported earlier that an IPO could value Mobileye at more than $50 billion.

The stock soared in the premarket after the company announced positive results from a late-stage trial of its experimental treatment for a genetic disorder that affects brain development in girls.

Jack In The Box was upgraded to a buy from a hold atDeutsche Bank, which said the restaurant operator's acquisition of Mexican food chain Del taco makes sense. Jack In The Box shares fell after the deal was announced. Jack In The Box was up in premarket trading.

J.P. Morgan Securities upgraded the stock to "overweight" from "neutral" after a meeting with management. The firm said it was more confident in the growth of the app.