Circadian clock made from scratch to probe how biological rhythms work

Computer model of the molecular structure and function of the circadian clock Kai protein in cyanobacteria LAGUNA PHOTO LIBRARY
In a test tube, a circadian clock was recreated in its entirety. This is the first time that a cellular pacemaker has ever been created outside of a living organism.

Carrie Partch, University of California Santa Cruz and her colleagues invented the clock from a cyanobacteria. It is composed of six proteins and can function for many days without human intervention. The record so far is probably two weeks.