Barack Obama made fun of his left-handedness when he entered office.Obama signed the Affordable Care Act on March 23, 2010 in the East Room at the White House. J. Scott Applewhite/APObama laughed when he signed his first executive orders.Surprisingly, many US presidents are left-handers. Research suggests that lefties are more creative and better at "divergent thought," generating new ideas from existing information. They also face challenges better.