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Salwa Eid Naer, the World 400m Champion, will not be able to compete in Tokyo Olympics because she was banned for two years for violating anti-doping regulations.
After failing out-of-competition testing, the 23-year-old Bahraini was sanctioned.
To claim the 2019 world title, she ran 48.14 seconds.
The Court of Arbitration for Sport (Cas), upheld an appeal against the World Athletics Disciplinary Tribunal's decision to dismiss the charges in Oct 2020.
The World Championships results, where she was the third fastest in history, will be preserved.
The ban will be in effect from Wednesday, 2023 to early 2023. Naser has been temporarily suspended from 4 June 2020 to 14 Oct 2020.
Naser was initially charged with having missed four anti-doping testing between January 2019 and January 2020.
After an investigation, it was determined that the doping control officer had been to the wrong address and she was guilty of three failures in whereabouts. However, the tribunal dismissed her missed test on April 12, 2019.
Naser was found guilty by the CAS panel of violating Article 2.4 of IAAF's anti-doping rules.
"Naser is sanctioned with a two-year period of ineligibility, beginning on the date of notification of this award with credit for the provisional suspension already served between April 4 2020 and October 2020," CAS stated in a statement.
"All Naser competitive results from 25 November 2019 through the date of notification will be disqualified with all the consequences including forfeiture or ranking points, medals, prize money, and prize money.
To claim the 2019 world 400m title, Naser ran the fastest time ever in history.
The panel was not asked to declare whether the athlete was or wasn't a doping cheat, but to determine if she was in violation of anti-doping laws as charged and to impose the appropriate sanction.
"The panel found her in breach, and that her entire approach to the whereabouts requirements throughout 2019 and January 2020 was seriously and inexcusably irresponsible."
CAS stated that her career was at fault and she is to blame.
The panel stated that she tried to avoid the consequences of her actions by giving evidence that this panel found untruesful.
"This approach by a top-level athlete is seriously detrimental to the anti-doping program, and it is sanctioned accordingly."
The Tokyo Games will be missed by the Nigerian-born runner. Next year, Oregon's World Athletics Championships will also be missed.
"I have never been a cheater." In June 2020, Naser stated that he will not be a cheat. I only missed three drug screenings, which is quite normal. It happens. Anyone can experience it. Because I wouldn't cheat, I don’t want anyone to be confused by all of this.
"I wouldn't take performance-enhancing drugs. I believe in talent and know that I have it.