Breonna Taylor posthumously made history by landing on the cover of Oprah's Magazine ... the first time EVER in the magazine's 20-year history O herself was not front and center.

Oprah stepped aside for one of her final print editions ... dedicating the September cover with Breonna's image, declaring, "If you turn a blind eye to racism, you become an accomplice to it." These words are emblazoned on the cover ... "HER LIFE MATTERS."

O dropped the news on Insta ... where she gave a touching tribute to Breonna ... "She was just like me. She was just like you. And like everyone who dies unexpectedly, she had plans. Plans for a future filled with responsibility and work and friends and laughter."

Oprah went on, "I think about Breonna Taylor often. Imagine if three unidentified men burst into your home while you were sleeping. And your partner fired a gun to protect you. And then mayhem. What I know for sure: We can't be silent. We have to use whatever megaphone we have to cry for justice. And that is why Breonna Taylor is on the cover of @oprahmagazine."

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