A study shows that people with type A blood groups are more likely to have a stroke before the age of 60.
Red blood cells have a lot of chemicals on their surface. A and B can be present together asAB, individually as A or B, or not present at all.
There are subtle differences in the genes responsible for the major blood types.
A correlation has been found between the A1 subgroup and early-onset strokes.
About 17,000 people with a stroke were included in the data from 48 genetic studies. The people were between 18 and 59 years old.
Two locations were found to be associated with an earlier risk of strokes. There is a spot where genes for blood type are located.
A second analysis of specific types of blood type genes found people with a variation of the A group had a 16 percent higher chance of a stroke before the age of 60.
The risk was lower for people with the O1 genes.
There is no need for screening or vigilance for people with type A blood who have a small risk of stroke.
Steven Kittner from the University of Maryland said that they don't know why blood type A is riskier.
It's likely that it has something to do with blood-clotting factors such as platelets and cells that line the blood vessels, all of which play a role in the development of blood clot.
The results of the study may seem alarming, but let's remember that there is more to this than meets the eye.
Over one million people in the US suffer a stroke each year. Three out of four of these events occur in people 65 years and older.
35 percent of the people in the study are from non-European countries, with the others living in North America, Europe, Japan, Pakistan, and Australia. Future studies with a more diverse sample can clarify the significance of the results.
More follow-up studies are needed to clarify the mechanisms of increased stroke risk.
People who had a stroke before the age of 60 were more likely to have one after the age of 60.
The researchers used a database of 9,300 people who had a stroke and 25,000 people who didn't have a stroke.
The increased risk of stroke in the type A blood group became insignificant in the late-onset stroke group, suggesting that strokes that happen early in life may have a different mechanism.
The authors say that strokes in young people are less likely to be caused by a build-up of fat in the arteries and more likely to be caused by clot formation.
The study showed that people with type B blood were more likely to have a stroke than people without the blood type.
According to previous studies, the part of the genome that codes for blood type is associated with cardiovascular problems.
A and B blood types have been found to have a slightly higher risk of blood clot in veins.
The paper was published in a medical journal.
The first version of this article was published in September of 2000.
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