The company said Monday that it had cut ties with the player.
The Brooklyn Nets star is no longer under contract with the footwear giant after he shared antisemitic content on social media.
There was no further comment from a Nike spokesman.
The decision was mutual according to Shetellia Riley Irving.
She said that they decided to part ways and wished Nike the best.
Irving did not comment on the news but did post a video on the social networking site that appeared to reference the severed contract.
The video says that being free is priceless.
The decision to sever ties with Irving comes just a month after Nike suspended its agreement with the guard and said it wouldn't be releasing the newest version of his sneakers.
The company said in a statement that it condemns any form of antisemitism.
Phil Knight said in an interview that he thought Irving stepped over the line.
It was supposed to be released in late November. Irving has been with Nike for three years.
Irving was suspended for at least five games by the Brooklyn Nets because he failed to say he has no antisemitic beliefs.
NBA Commissioner Adam Silver had sought an apology from Irving and when one didn't come, he said the athlete is " currently fit to be associated with the Brooklyn Nets."
Irving apologized on his account. He told reporters that he doesn't "stand for anything close to hate speech or antisemitism."
When things are assumed about us and we don't have an opportunity to speak for ourselves, it's necessary for me to stand in this place and take accountability for my actions.
After making antisemitic statements, Ye was dropped from Adidas and Gap.
On Halloween, the musician defended Irving on social media.
Ye wrote that there are some real ones still here.
Irving came back to the Nets after missing eight games. The Nets are in the middle of the pack in the NBA.