JP Morgan Chase andDeutsche Bank have been sued by two women.
They say the banks benefited from the late financier's sex-trafficking operations.
He was awaiting trial on sex-trafficking charges when he took his own life.
The suits were filed in New York.
Dozens of the dead billionaire's accusers have been represented by lawyers.
The women who are seeking financial damages are not named in the filing, which was first reported by the Wall Street Journal newspaper.
According to the claims in the lawsuit filed against JP Morgan Chase, one woman, who was a former ballet dancer, was abused by a group of people.
It claims that JP Morgan knew that its accounts were being used for traffickers because of the identities of the people who withdrew large sums of cash.
When contacted by the news, JP Morgan Chase refused to speak.
A woman claims in a lawsuit that she was forced to have sex with a man for 15 years.
In some cases, the woman would be paid in cash for sex acts.
When ties were severed with JP Morgan, the lawsuit claims, the wealthy Epstein turned to the German bank.
Previous findings by New York banking regulators aboutDeutsche Bank's business with Epstein are referred to.
Although the bank classified Epstein as high-risk, it failed to scrutinize the activity in the accounts for the types of activity that were implicated by his past.
The bank admitted that it made a mistake when it took on the client.
The spokesman for the investment bank said that they will present their arguments in court.
Wealthy individuals and financial institutions helped Eisenstein and his co-conspirators. We will continue to fight until everyone is held accountable. This isn't the end.
The time has come for his wealthy friends and the financial institutions that played an important part in his downfall to be held responsible.