Tel Aviv University has developed a new technology that can be used to destroy cancer tumors. According to the research team, this latest technology enables the destruction of the tumor in a non-invasive way.
In collaboration with Dr. Dov Hershkovitz of the Department of Pathology, the study was led by a PhD student. Agata Exner is a professor at Case Western Reserve University. There was a study published in the journal.
"Our new technology makes it possible, in a relatively simple way, to inject nanobubbles into the bloodstream, which then congregate in the area of the cancer," said Dr. Ilovitsh, who is a professor of medicine. After that, we use a low- Frequency Ultrasonic to destroy the Tumor.
The method of cancer treatment today is surgical removal of the tumors in combination with other treatments such as chemotherapy and immunotherapy, according to the researchers. It is possible to destroy a cancer with a non- surgical method.
There are two advantages and two disadvantages to this method. On the other hand, it is possible to produce thermal or mechanical effects by delivering powerful acoustic energy to a focal point with high spatial-temporal precision. Solid tumors can be effectively treated with this method. It's possible to treat patients who aren't good candidates for surgery. The disadvantage is that the heat and high intensity of the waves can damage the tissues.
Dr. Ilovitsh and her team tried to find a solution to this problem. In the experiment, which used an animal model, the researchers were able to destroy the tumor by injecting nanobubbles into the bloodstream, as opposed to what has been until now, which is local injection of microbubbles into the tumor itself.
A more specific targeting of the area of the tumor and reduced off-target toxicity can be achieved with the combination of low Frequency Ultrasonic Waves and Small Particles. The swelling and explosion of thenanobubbles can be caused by applying the low frequencies. It's possible to destroy tumors at low pressure. The advantages of our method include being safe, cost-effective, and clinically available, as well as the fact that it can be used to target tumors with the help ofultrasound.
Dr. Ilovitsh says that the use of low-frequencyechocardiography enlarges the focal point and increases the depth of penetration. It can help in the treatment of tumors that are located deep with the body. It is likely that the treatment will be effective with other types of tumors, and in the future, also in humans, even though the experiment was conducted in a breast cancer tumor mouse model.
The CEO of Ramot says that the company applied for several patents to protect the technology. We believe in the commercial potential of this breakthrough technology and we are in contact with several leading companies in Israel and abroad to promote it.
There is more information on the Low Frequency Ultrasonic Mechanotherapy for Non Invasive Cancer Surgery. It is titled: 10.1039/D2NR03C.
Journal information: Nanoscale
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