The capsule is set to break the space agency's record for distance traveled by a spacecraft designed for astronauts after reaching within 80 miles of the moon's surface.
After emerging from behind the moon, the capsule sent images of the Earth to flight controllers.
After a slingshot over the moon's surface, the capsule will begin its journey back to Earth.
During its journey, the spaceship will reach a point more than 270,000 miles away from the Earth.
The journey to the moon will take over a month.
A total of $49.90 billion. That's how much NASA has spent on the project since it started. The cost of each launch is estimated.
If the current flight is successful, a subsequent launch will return astronauts to the moon for the first time in 42 years.
According to its website, NASA wants to take humans farther than they have ever traveled before. Last week's launch of the Artemis 1 rocket is the first in a series of launches that aim to put humans on the moon. The agency wants to establish a long term presence on the moon and eventually Mars.
The last big step before the moon.
The Artemis 1 mission takes off towards the moon.