The Artemis is going to the moon.
The capsule will travel over the moon's surface before entering a bigger circle.
This maneuver will take place on the far side of the moon and the vehicle will be out of contact.
The Artemis team said they would be watching for the signal and so far the mission had exceeded expectations.
"It's been a really exciting few days for the team and the spacecraft as we learn how the system operates in the deep space environment," said Jim Geffre.
This is the first time in 50 years that a human exploration vehicle has left Earth and gone to the moon.
The landing sites of Apollo 11 and Apollo 12 will be looked over by the craft. When it's out of contact for 34 minutes, it will send back data and video from the fly-by.
The most powerful rocket Nasa has ever built was used to launch the Artemis mission.
The moon was placed on a path. Several selfies have been sent back by the capsule.
Three manikins covered in thousands of sensors are making the journey because no astronauts are on board this time.
Zena Cardman explained that the sensors are trying to figure out if the environment will be good for people.
There are a lot of things that we as humans care about.
If this flight goes well, astronauts will join the next ride, which will take the first woman and first person of colour to the moon, before a third Artemis mission.
The European Space Agency is keeping a close eye on the craft. The service module is used for the voyage.
The passenger on the plane is a British stop-motion animated character. The person is strapped in for the ride. The crew capsule has a mascot who is floating in it.
After the close flyby, the moon will begin to circle around it.
When it reaches 400,171 km from Earth, it will break Apollo 13's record.
It will have traveled more than 270,000 miles from our planet in two days.
The capsule will return to the Moon and then on to Earth with a splashdown in the Pacific Ocean on 11 December.
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