Harry Kane was replaced in the second half of the Carabao Cup loss atNottingham Forest.
England's opening World Cup game against Iran is 12 days away.
The England squad will be named on Thursday.
"Kane would be okay, it was a problem of exhaustion," said the coach. Harry played every game and it's normal for him to be tired.
Kane made his 21st consecutive start for Spurs in the third round of the EFL Cup.
He was replaced after 59 minutes despite the fact that Spurs were behind by two goals.
Kane stopped himself to recover energy after a soft training session yesterday.
He waited until Wednesday morning to make a decision on starting Kane.
He said that other players could tell him that they didn't want to help the team.
One could be selfish and not think about the World Cup. Harry Kane showed to be a good person.
What's happening in this period is normal.
England captain Kane, who is just two goals away from equalling Wayne Rooney's goal- scoring record for the national team, is certain to be named in the World Cup squad on Thursday.
Iran and England will face off on November 21.