by Jacobs University.

Coffee could offer protection from catching COVID-19
Published structure of Spike protein ACE-2 complex. Overall structure of the RBD-ACE2-B0AT1 complex. (A) Cryo-EM map of the RBD-ACE2-B0AT1 complex. (B) The overall structure of the RBD-ACE2-B0AT1 complex. The figure is taken from Yan et al. (2020). Credit: Food & Function (2022). DOI: 10.1039/D2FO00394E

Is it possible to protect yourself against coronaviruses by drinking a cup of coffee? According to research, what has not been proven in practice is plausible.

The chemical compound 5-caffeoylquinic acid was shown in the laboratory to be found in chlorogenic acid.

A cup of coffee in a laboratory setting contains 100 milligrams of 5-caffeoylquinic acid. In the laboratory, 5-caffeoylquinic acid in this concentration was shown to be high enough to prevent the docking of the spike protein to the ACE-2receptor. Further research is needed to prove that this process works.

The effectiveness of 5-caffeoylquinic acid will be determined by further studies. We can't answer the question of whether drinking coffee could protect against infections. We can say it's plausible. The chemist says that many people drink coffee and that it has a lot of positive effects. Coffee drinkers are less likely to suffer from diabetes.

A new measurement technique was needed for the studies on the effect of 5-caffeoylquinic acid on the spikeprotein. A detailed description of this method was published by the team.

The interaction between coffee and the coronaviruses will now be communicated to a wider research community. "Epidemiological studies could determine if regular coffee drinkers become more likely to be exposed to corona or not." Implications for long COVID could also be looked at here.

Dorothea Schmidt and her team are investigating the interaction between food and function. The DOI is 10.1039/ D2FO00394E.

It was provided by Jacobs University.