A report by a leading medical publication has found that climate change is affecting people's health.
According to the report, the world's continued reliance on fossil fuels increases the risk of food insufficiency.
Global leaders need to match action to the problem, according to the UN Secretary General.
The leaders will meet in Egypt for the conference.
The report is led by University College London and contains the work of 99 experts.
Extreme weather has increased pressure on health services around the world.
The last two decades have seen an increase in heat-related deaths.
In July of this year, 40C was recorded in the UK, as well as parts of Europe, Pakistan and China, setting a new temperature record.
Extreme heat can cause health problems such as cardiovascular and respiratory disease, heat stroke, and poor mental health.
There are solutions according to it. "Despite the challenges, there is clear evidence that immediate action could still save the lives of millions, with a rapid shift to clean energy and energy efficiency."
80% of global greenhouse emissions are produced by the G20 countries, according to Mr. Guterres. They need to invest more in renewable energy in order to lead the way.
He said that human health, livelihoods, household budgets and national economies are being decimated by the fossil fuel addiction.
The report today is a call to action.
The evidence presented shows the need for urgent action at the UN conference in Egypt.
The summit is facing a lot of challenges.
Developing countries will demand that nations that grew rich using fossil fuels cough up more money to meet the costs of climate change.
They will ask about the $100 billion a year that was supposed to be made available from 2020. We are a long way from the total.
The Egyptians host of COP 27 have warned of a crisis of trust.
The developed world is in a cost-of-living crisis. Billions of dollars are being spent on military support forUkraine.
Prepare for some heated discussions in Egypt.
Unicef warned on Wednesday that urgent action is needed to protect children and vulnerable communities from worsening heatwaves.
The spread of infectious diseases has gone up due to the change in climate. In the past 60 years there has been an increase in the number of months that facilitate malaria transmission.
Air pollution is caused by Fossil Fuel Emissions. Exposure to air pollution contributed to over five million deaths in 2020, of which over three million were related to fossil fuel burning.
Climate change is worsening the effects of other crises such as energy poverty and air pollution.
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