The National Health Service believes it will be able to prevent all new cases of HIV by the year 2030.
Those with drug-resistant infections will be able to get fostemsavir after it was approved last week.
For people with HIV in regions where they have not always been confident in receiving the best treatments, the new treatments will end uncertainty.
It was approved for use in January of this year and only needs to be injected every two months, unlike pills which need to be taken every day and can lose effectiveness permanently.
The goal of HIV treatment is to keep the number of virus particles in the blood so low that it can't be detected or spread.
The first healthcare system in the world to reach zero new cases of HIV will be achieved thanks to the effectiveness of these HIV drugs.
Professor Stephen Powis, the national medical director of the National Health Service, said: "We now have a genuine chance of achieving no new HIV infections, thanks to the unparalleled efforts of NHS staff and our ability to get effective drugs into the hands of the people who need them." The National Health Service proved it could strike deals with drugs companies that offered world-leading care at a price that offers the best value for taxpayers.
He said that the new national agreement for HIV drugs, along with better testing, diagnosis and support are leading the fight against the disease.
The number of new HIV diagnoses fell to 2,955 last year, the lowest number in a decade. The number of transmissions decreased by 34% over the course of two years due to better treatment and better access to preventative drugs.
The National AIDS Trust warned last year that there were significant inequalities in access to HIV care for people from black African and Asian background.
The charity said that the number of people with undiagnosed HIV has fallen from 5,560 to 4,660 in the last year. Between 4,980 and 6,960 were the number of people with HIV who weren't seen.
London is home to about a third of all people with HIV.