The Mercedes driver was the fastest in the first practice.
Hamilton defeated Verstappen by 0.084 seconds.
When the track would have improved in grip, their times wouldn't be as bad as Hamilton's.
Hamilton's team-mate George Russell was fourth, while Leclerc and Perez were fifth and sixth, respectively.
The second car of Carlos Sainz was sixth in the race after a couple of close calls with the walls.
The session was stopped for five minutes after Lance Stroll crashed at Turn 5.
Alpine's Ocon and Alonso tested an upgrade that they hope will improve their performance.
After his first run, Alonso's running was cut short by a gearbox oil leak.
Alpine and McLaren have made improvements to their cars as they fight for fourth place in the championship.
McLaren has a lot of changes around the sidepods and floor design.
Verstappen needs to win the race in order to win the title.