Trent Alexander-Arnold wasn't included in the England squad for the match against Germany.
Alexander-Arnold, who missed last year's Euros through injury, was not used in Friday's defeat by Italy.
James Ward-Prowse also misses out.
Ivan Toney is expected to make his international debut.
He received his first England call-up this month but wasn't included for the Italy game.
Jack Grealish is out of the Three Lions' squad due to a suspension.
squad selections are not the reason for the other omissions.
Alexander-Arnold has created the most chances by an English full-back this season with an average of 2.6 per match.
He has scored two goals and played more minutes than any other English full-back.
| Player | Minutes | Goals conceded | Minutes/goals conceded | Duels | Duel success |
| Ben Chilwell | 193 | 1 | 193.0 | 23 | 52.2 |
| Kieran Trippier | 681 | 7 | 97.3 | 44 | 50.0 |
| Reece James | 630 | 9 | 70.0 | 63 | 63.5 |
| Tyrick Mitchell | 414 | 6 | 69.0 | 34 | 38.2 |
| Trent Alexander-Arnold | 737 | 12 | 61.4 | 39 | 48.7 |
| Kyle Walker-Peters | 629 | 11 | 57.2 | 89 | 51.7 |
| Rico Henry | 630 | 9 | 52.5 | 53 | 49.1 |
| Luke Shaw | 154 | 6 | 25.7 | 14 | 50.0 |
AC Milan's centre-back Tomori did not play against Italy.
Instead, the manager chose to start Harry, who has made just three appearances in the league this season.
| Player | Minutes | Goals conceded | Minutes/goals conceded | Duels | Duel success | Interceptions per 90 minutes |
| Conor Coady | 531 | 4 | 132.8 | 23 | 47.8 | 0.8 |
| Ben White | 559 | 6 | 93.2 | 48 | 62.5 | 1.0 |
| Eric Dier | 810 | 9 | 90.0 | 47 | 48.9 | 1.6 |
| Fikayo Tomori | 744 | 9 | 82.7 | 49 | 61.2 | 0.8 |
| John Stones | 551 | 7 | 78.7 | 24 | 79.2 | 0.3 |
| Marc Guehi | 630 | 9 | 70.0 | 43 | 55.8 | 1.0 |
| Kyle Walker | 612 | 9 | 68.0 | 32 | 65.6 | 0.9 |
| Tyrone Mings | 540 | 8 | 67.5 | 27 | 74.1 | 1.0 |
| Harry Maguire | 281 | 7 | 40.1 | 24 | 50.0 | 1.9 |
The match at Wembley is England's last before they announce their squad for the World Cup in December.
England were demoted from their Nations League group after Friday's loss in Milan.
Alex is a sports reporter for the British Broadcasting Corporation.
The omission of Alexander-Arnold shows that he is not in the England right-back spot.
When England play a back four, Kyle Walker is one of the back three. It can be argued that Trippier is ahead of Alexander-Arnold because of hisVersatility and also because of the attacking threat he offers.
Alexander-Arnold is one of the best passers of the ball in England and there is no doubt about it. With England, he doesn't have the same freedom as with his club.
He has justification for preferring certain players because his approach has helped England reach a semi-finals of a World Cup and a first final in a European Championship. Alexander-Arnold was injured and missed the Euros.
Being left out of the last matchday squad will be a big blow for him and one that will be felt more because he did not come off of the bench in Italy.
After the international break, Alexander-Arnold's place in the squad is questionable.
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