The new moon rocket will not be launched on Tuesday due to concerns about a tropical storm headed to Florida.
It is the third delay in the past month for the lunar-orbiting test flight featuring mannequins but no astronauts, a follow-up to the Apollo moon-landing program of a half century ago.
Technical issues and hydrogen fuel leaks were the cause of the previous scrubs.
Ian is currently a tropical storm in the Caribbean and is expected to become a Hurricane by Thursday.
The cone shows the probable path of the storm and includes the Kennedy Space Center.
Nasa decided on Saturday to forgo Tuesday's planned launch attempt and instead prepare the 322-foot rocket for a possible return to its hangar. Managers will make a decision on Sunday.
If the rocket is still at the pad, the last chance for a launch will be on 2 October. It's possible that the test flight will be pushed into November if there is a late Sunday or Monday roll back.
The Artemis I test flight is a major turning point for the post-Apollo human spaceflight program.
Artemis will be heading to the moon as a stepping stone for a future trip to Mars. The rocket is the most powerful ever built.
If the first test flight goes well, the next mission will lead to a two person moon landing in 2025.
The report was contributed to by Associated Press and the news agency.