Will Jimmy G and the 49ers score a big road win vs. the Broncos? (1:15)

Ryan Clark thinks the 49ers will win against the Broncos. There is a break between 1:45 and 1:45.

5:22 PM ET

George Kittle had the best day of his career when he played for the 49ers against the Broncos. Kittle's return from the groin injury that kept him out for the first two weeks of the season could not come at a better time.

Kittle will make his season debut against the Broncos.

He's good to go, according to Shanahan. He was getting better each day. The run and pass game are important to him. Kittle has been a good player for us over the years. We need to get him back into football shape just because he hasn't played in a while, but he helps us in so many ways.

Kittle participated in the first two sessions on a limited basis and went in full Friday. On the Friday injury report, he had no injury designation.

Kittle said he's happy. I just had a refreshing breath of fresh air. It's nice to be back on the field. I enjoy working with our staff. I wouldn't mind if they didn't see us for the rest of the season. It's great to be back out there catching the football and hitting people.

The Niners had a bonus practice before the season opener to help Kittle recover from his groin injury. He did not play that week or last week and did not participate in practice for the first time that day.

With Kittle back, Jimmy Garoppolo will have his full complement of pass catchers in his first start of the season. The Niners don't mind if Kittle recreates his performance from the last time they met.

Kittle had seven catches and a touchdown in the San Francisco win. Kittle was shut out in the second half, which left him just shy of Shannon Sharpe's record for receiving yards by a tight end in a game.

Kittle is excited to be back on the field regardless of the opponent.

Kittle said that Sunday Night Football is for that. Let it all out there. It's going to be enjoyable.

Arik Armstead is a defensive lineman for the 49ers. The status of Armstead is up in the air because he is dealing with a foot injury. Armstead didn't practice this week.