Report: 49ers' Trey Lance to Have Surgery on Significant Ankle Injury; Out for Season

San Francisco 49ers quarterback Trey Lance reportedly will miss the remainder of the season after suffering a "significant" ankle injury that will require surgery.

Lance was carted off the field in the first half of the game.

In the team's Week 1 loss to the Chicago Bears, Lance was just 13-of-28 for 164 yards, one touchdown and one pick-six.

He suffered a left knee sprain during his first career start last year, a Week 5 road loss to the Arizona Cardinals. The second-year signal-caller played sporadically for the Niners while serving as the backup to Jimmy Garoppolo.

In all, the third overall pick in the 2021 NFL draft recorded 603 passing yards, 168 rushing yards and six total touchdowns across six games in his debut campaign.

The 49ers will be led by Garoppolo for the rest of the season.