The unanimous-decision victory was the result of a three-round fight on Sunday.
The scores were 114-108, 112-108 and 114-109.
With the victory, Ruiz is in line for a shot at the title held by Tyson Fury, who is in talks to fight Oleksandr Usyk. Next year, there is a chance for a Ruiz vs. Deontay Wilder match up.
If Deontay wins in October, I and him will have the same management and we can make this fight happen. Let's start it." I want to bring the title back to Mexico.
In the second round, he scored a couple of knockdowns and showed off his power. The first knockdown was the result of a right hand that connected on Ortiz's temple and seemed to affect his balance for the rest of the fight.
The second knockdown seemed to be questionable, with no punch landing.
He used his southpaw jab to control distance. Every time, Ruiz won the exchanges. The shots affected the 43-year-old time and again.
In the second round, the Cuban was on wobbly legs but punched his way out of trouble and ended the round with a counter right hand. At the end of the first round, he hit Ruiz with a right hand. If it weren't for the knockdowns, the fight would have gone the distance.
He weighed 26834 pounds. I waited for him to counter when he did. There is a warrior in this picture. I did a great job fighting him. I show more class than I usually do.
The Southern Californian found the target again in Round 7 after another compact right hand, after he was knocked down in the 4th and 5th rounds.
A brutal straight right hand that connected in the waning moments of Round 11 caused a badly damaged left eye for Ortiz.
In the 12th round, the underdog tried to get theKO but never really threatened Ruiz.
The defeat is Ortiz's second in four fights, the other being a highlight-reel knockout at the hands of Deontay Wilder. In their meeting in the year 2018, he was also stopped by the man. The fight was rated No. 8 at the time.
"Everyone that said 'King Kong' is old, I gave you a war today," said Oritz, who survived two knockdowns on New Year's Day. I would like a second chance. I kept my hands up so my vision was unaffected. Do you think it's over? Tonight, you saw a warrior.
There is a chance for another shot at the title. One of the biggest upsets in the history of the division was when he defeated Anthony Joshua.
When he faced Joshua again six months later, he dropped his three titles due to his weight.
Since that December night in Saudi Arabia, he's fought two times: a decision win over Chris Arreola last May, and now a victory over Victor.