| Venue: Flushing Meadows, New York Dates: 29 August-11 September |
| Coverage: Daily radio commentaries across BBC Sounds and the BBC Sport website and app, with selected live text commentaries and match reports on the website and app |
On an entertaining night in New York, Nick Kyrgios ended the defending US Open champion's reign with a four-set win.
In his last 16 win, the Australian demonstrated all of his shot-making and propensity for creating drama.
The world number one will lose his ranking after the loss.
The Wimbledon runner-up will play the 27th seed Karen Khachanov in the quarter- finals.
The 12th seed from Spain was defeated by the third seed from Russia in a Grand Slam quarter-final.
"Daniil is the defending champion and a lot of pressure on his shoulders, but I've been playing amazing recently, I'm moving back into the world's top 20 after the win."
This was the biggest blockbuster of the tournament so far and a match-up between two entertaining players which would have been fit for the later stages.
The players promised to put on a show on the Sunday night of the holiday.
They didn't let us down.
Almost three hours of ferocious serving, baseline blows, momentum swings and bizarre moments entertained a crowd on a sticky night.
"It was a really high-level match, and I compared it to those two guys," said Medvedev.
He has a good chance of winning the tournament if he plays like this. It's not certain because he's going to get tough opponents.
The first set was a battle of-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873-8873--8873-8873-8873-8873-8873-8873-8873-8873-8873
A tense tie-break, packed with quality and drama, saw Nick Kyrgios save three set points and twice clatter his racquet against the court before converting the fourth chance of his own to take the lead
After the opening set, which took 64 minutes, a shirtless Medvedev complained to the umpire that the noise from the Australian's box was making him feel unwell.
The crowd that supported him wanted to see the one that came out.
With his first serve percentage dropping, he played with nonchalance, and fell behind.
The show resumed after a break. He slipped at 30-15 in the next game and looked injured as he lay on the court, prompting Medvedev to check on him.
There was an extraordinary moment in the next point when the pair tapped hands after the player reassured them he was okay.
After forcing the Russian into a volley which was looping out on the Russian's side of the net, Kyrgios came around the post to hammer it into the court.
He lost the point because of the foul shot, which meant he didn't get the break-point opportunity.
The moment that felt like a significant and perhaps pivotal moment was when Kyrgios broke for 3-1 and served out to win the match.
He showed how much he was in the zone when he popped off the court.
He jumped off his seat and kept going as he raced into a big lead.
Many of the crowd rose to their feet as he thumped an ace down the middle to seal the victory.
The rivals shared an embrace full of shoulder-patting as he drew applause and then joined the crowd in clapping his opponent back to the locker room.
Matteo Berrettini qualified for the quarter-finals for the second year in a row with a five-set win over Alejandro Davidovich Fokina.
Berrettini, who upset Andy Murray in the previous round, defeated the Spaniard 3-6, 6-7, 6-3, 6-2.
Davidovich Fokina was hurt in the fifth set when he was behind 4-2.
Berrettini will face the winner of the France-Norway match.
The lucky loser was eliminated in the fourth round of the Grand Slam.
Stephane Robert was the last man to play in the last 16 at a Grand Slam.
Four players are vying to be world number one at the end of the tournament, and one of them is ranked seventh in the world.
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