monkeypox lesions in a coinfected patient
Monkeypox skin lesions: small vesicles (Panel A), reddened haloed pustules (Panel B and Panel C) and umbilicated plaques (Panel D). After 16 days, the lesions had almost healed, leaving a small scar (Panels E to H).Journal of Infection
  • A patient in Italy was the first to be diagnosed with all three diseases at the same time.

  • He had a sore throat and a rash after returning from Spain.

  • The man had sex with other men while on vacation.

The man who tested positive broke out in a rash. According to a case study, he had monkeypox and HIV.

The 36-year-old patient, who was not identified by name in the report, is the first person in the world to test positive for all three infections in one day.

Nine days after he returned from Spain, the Italian man developed a sore throat, headaches and a high temperature. He had a positive test for COVID-19 on July 2, and his symptoms quickly got worse.

The man saw a rash on his arm. He had blisters on his face, torso, legs, and backside. The blisters continued to grow and the man decided to go to a hospital in Italy.

The man was diagnosed with a coinfection of COVID-19, monkeypox, and HIV just a few days after his first symptoms. The importance of testing for other sexually transmitted infections after a diagnosis of monkeypox is underscored by his case.

'Suggestive' skin lesions and recent travel

When he arrived at the hospital, the man's body looked like it had been bitten by a monkey. The side of his foot and palm of his hand were covered in blisters. One of the telltale signs of the virus was the turning of other sores into scabs.

The perianal region has been affected by the recent outbreak. The outbreak has mostly affected men who have sex with men in their intimate regions, so experts think there is a chance of sexual transmission.

After the patient disclosed that he had had sex with other men while on his vacation to Spain, doctors ordered him to have a full STD test at the hospital. The man's medical history shows that he was negative for HIV as of September 2021.

Based on his sexual history and immune markers, it's likely that he was recently diagnosed with HIV.

Doctors wrote in the report that sexual intercourse was the main way of transmission of monkeypox.

The man received treatment for COVID and HIV

Doctors don't know how the infections of COVID-19, monkeypox, and HIV will affect a patient.

After a few days in the hospital, the Italian patient recovered from his monkeypox, with almost all of his skin peeling off. He got an injection of Sotrovimab to treat his COVID infection and it worked.

Most of the man's symptoms had dissipated by the sixth day. He had no new skin diseases and was discharged to home isolation.

The patient's sores healed almost completely when he came back for a second visit. He did not need to be treated for monkeypox, although some doctors may recommend TPOXX for people with compromised immune systems.

The patient was put on a combination of drugs to fight the HIV in his body. He needs to take the medication to keep the disease at bay.

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