Chemical distress signals can be sent out from the dying tissue of a disease, says Lagasse. In cases of severe disease, these signals don't work. The signals seem to help along the growth of the tissue in the other side of the body.
Gouon-Evans said it was amazing. There is an incubator in the body that can be used to grow organs.
Five years ago, Lagasse, Hufford, and Fontes founded the company to take the technology to the next level. The team is trying to figure out how to grow new organs with the help of the immune system.
The company is focused on the health of the people. Over the last 10 years, members of the team have collected promising evidence that suggests they can use their approach to grow new mini livers in animals. The body has an internal regulator that stops the growth of the mini livers at a certain point in time.
The research done by the team shows that most of the cells injected into a lysosomes will stay in the lysosomes but some will migrate to the liver. The cells can help regenerate the tissue. According to Lagasse, when this happens, there will be a new miniLiver in the Lymph node that will shrink and keep the total amount of tissue in balance.
The blood supply to the liver is diverted in pigs and dogs, which causes the organ to die. The animals will eventually be saved by injecting their cells into the lysosomes in their immune system.
In the pig study, the team first removed the blood supply from the animal's body. The team injected the healthy cells into the pigs. The doses ranged from hundreds of millions of cells to billions of cells.
All the animals appeared to have recovered from their injuries. The tests suggested that their liver function had gotten better. When the team performed autopsies on the animals, the new organs looked like miniature healthy livers, each up to 2% of the size of an adult. It takes around three months for the treatment to make a difference.