The building blocks of all living organisms are made up of genes. They are referred to as the workers of the cell, where they perform many essential tasks. The consequences of something going wrong are serious. Both research and health care have expressed the need for effective tools to analyze the functions and activities of proteins, and in a new article in scientific journal Nature Communications a technology that is expected to open important doors in cell and
MolBoolean is a method to determine levels of a pair of proteins in individual cells. In order to make the cells' activity status and communication more visible, we have continued to develop a tool that we created in 2006 that is used all over the world, and the functions that we are now adding that generate information about the relative amounts of different proteins as well as relative amounts of It is important to know whether the reviews are based on ten or 1,000 opinions.
The group's results are catching the attention of both academia and industry, and the company Atlas Antibodies is preparing the method for the market. In the long term, the tool is expected to improve the diagnosis and treatment of cancer.
To increase the knowledge of what happens in cancer cells, we want to develop tools to visualize processes within cells. When studying cell signaling, it's important to know the balance between free and interacting proteins, and that's why we wrote the article.
There is a group at the Faculty of Pharmacy. The work was done with researchers at the universities of Porto and Uppsala.
More information: Doroteya Raykova et al, A method for Boolean analysis of protein interactions at a molecular level, Nature Communications (2022). DOI: 10.1038/s41467-022-32395-w Journal information: Nature Communications
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