Gut Bacteria Could Be Evolving Inside Us to Escape The Intestine

According to a new study, Gutbacteria may be able to evolve over time to live outside of the intestine, which may make them more dangerous and cause inflammation in other organs in the body.

Scientists don't understand much about how the various biological mechanisms and chain reactions work, even though there is a lot of research explaining the positive and negative effects that gut microbes can have on our health.

The cause of some health issues is believed to be a 'leaky gut', where the intestine is more porous than it should be. There are a lot of unanswered questions about the condition.

There is a mystery about how potentially pathogenicbacteria can exist in healthy people for decades with no health consequences.

In an attempt to solve the mystery, Palm and his colleagues introduced a potentially pathogenic bacterium into germ-free mice with no gut microbes of their own. The mice were tracked for three months.

The researchers observed the evolution of thebacteria. One was similar to the original strain and the other had small genetic changes that allowed it to live in the gut.

The immune system can't seem to notice the mutatedbacteria in organs. In the experiments on mice, it was found that the presence of a certain type of microbes could lead to inflammatory responses.

Palm believes that the process of evolution begins in each new host due to the preferential transmission of non-pathogenic strains.

As some strains move on to other people, a niche may open up in the gut room, allowing other strains to evolve.

Scientists say that this phenomenon is known as 'within-host evolution' and is a possible explanation for whybacteria can adapt to different environments. Environmental factors have an influence on this.

The less space any one species has to grow, the less likely it is that it will develop into a harmful variant. Michael Palm, the study's senior author, said that anything that affects diversity, such as diet, could help explain the risk of inflammatory conditions.

We may be able to develop and introduce preventative therapies for these health problems if we can understand more about the evolution of the bacterium.

Palm says that thebacteria are pre-adapted to exist in other parts of the body

The research was published in a journal.