It is not often that a medical institute has to say it is unable to take calls because of overwhelming demand, but that was the case on Tuesday at the centre.

Since she was diagnosed with breast cancer at the age of 44,Newton-John has been one of Australia's most high-profile advocates for cancer research and treatment.

The impact of the entertainer on cancer research was far reaching.

The chief executive said thatOlivia was a pioneer in the cancer field.

She helped scientists advance scientific discoveries and gave hope to people affected by a cancer diagnosis.

She focused on the importance of physical, emotional and spiritual support for the person going through a cancer diagnosis as well as their family and friends.

Her legacy will continue in the work of world leading research, treatment and care.

Austin Health is a major public health provider.

In an interview with Guardian Australia, the chief executive of Austin Health said that the commitment of Newtown-John over the past decade had been important to Austin.

He said that the centre wouldn't be here without her. The success of the centre is due to her continued support.

Over the past decade, it has allowed us to provide care and support to thousands of patients.

In June of 2012 the ONJ centre opened as an outpatient ambulatory centre and later became a hospital.

It is involved in about 200 clinical trials for a wide range of cancers.

Olivia Newton-John in 1982. Shortly after her family’s announcement, tributes began pouring in from former costars.

After the death of an Australian star, people pay their respects.

The director of the Austin Health Foundation said on Tuesday that the centre wouldn't have been created if it wasn't forNewton- John.

There are no two ways about it.

She was proud of this and it was her legacy.

When I talked to her about it, she said it was better than any billboard she had seen.

She is so proud of what she has done with us.

John Easterling asked his followers to donate to the ONJ centre instead of flowers.

The entertainer underwent further treatment after she was diagnosed again.

In September of last year,Newton-John revealed that her breast cancer had spread to her spine.

She told the Seven Network that she was trying to treat the illness naturally.

The cannabis oil that was used to treat her pain symptoms came from Easterling's California marijuana farming business.

Australian access to medical cannabis is limited and fraught with bureaucratic obstacles compared to other countries in the Organisation for Economic Co-operation and Development.

Olivia Newton-John and John Travolta in Grease, 1978

A life and career in photographs.

Australian entertainment icons who have faced their own battles with cancer, like Delta Goodrem, have paid tribute to the UK-born singer, who made a Companion of the Order of Australia in 2019.

When I was 10 years old, I looked up to a person namedOliviaNewton- John. Minogue was diagnosed with breast cancer at the age of 36, but she never gave up.

She was an inspiration to me in a lot of ways.

Goodrem, who was diagnosed with Hodgkin's lymphoma at the age of 18 and who playedNewton-John in the miniseries Hopelessly Devoted to You, posted on social media that the world will feel this sad news.

I don't have all the words I would like to say, but I hope everyone will join in celebrating our belovedOlivia, her heart, soul, talent, courage, grace, I love you forever.

Goodrem started her own foundation in 2020 to raise money for blood cancer research.