According to the new research published in the Journal of Clinical Endocrinology & Metabolism, people with sedentary lifestyles and poor sleep habits could be at risk of developing a condition called fat deposits in the bile duct.

About a quarter of the adult population is affected by bile duct disease. Obesity and type 2 diabetes are some of the causes of this type ofliver disease. A major health and economic burden to society may be caused by bile duct diseases.

The Guangdong Provincial Key Laboratory of Food, Nutrition and Health is located in Guangzhou, China. The study found a 29% reduction in the risk for the disease due to a 29% improvement in sleep quality.

Snoring and daytime napping for more than 30 minutes were associated with an increased risk of the disease in Chinese people with it. A slight improvement in sleep quality resulted in a 29% reduction in the risk of fat deposits in the bile duct. The effects of poor sleep quality on people with sedentary lifestyles were more pronounced.

The study shows that even a moderate improvement in sleep quality is enough to reduce the risk for the disease. The study calls for more research into the field of sleep quality and strategies to improve it.

The Guangdong Provincial Key Laboratory of Food, Nutrition and Health is one of the authors.

Funding for the study came from the National Key R&D Program of China, Sun Yat-sen University, the Key Project of Medicine Discipline of Guangzhou, and the Basic Research Project of the Key Laboratory of Guangzhou.

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  1. Jialu Yang, Shiyun Luo, Rui Li, Jingmeng Ju, Zhuoyu Zhang, Jichuan Shen, Minying Sun, Jiahua Fan, Min Xia, Wei Zhu, Yan Liu. Sleep factors in relation to metabolic-dysfunction associated fatty liver disease in middle-aged and elderly Chinese. The Journal of Clinical Endocrinology & Metabolism, 2022; DOI: 10.1210/clinem/dgac428