When hair follicle cells divide, a single chemical is needed. Follies are a source of stem cells and could be used to treat baldness.
The majority of cells in the human body are the same as they were when they were born. A blood cell can't be turned into a nerve cell. Stem cells are similar to blank tiles in a game of Scrabble in that they can turn into other types of cells.
They can be used to repair damaged tissue or organs.
Stem cells are thought to allow characters in science fiction to heal quickly from injuries.
The new research will help us understand stem cell behavior so that we can control it and promote wound healing. The research is detailed in a journal.
The stomach and liver are able to heal themselves after being wounded. The only organ in humans that regenerates automatically and periodically is the hair follicle.
The process by which cells in hair follicles, including stem cells, divide and form new cells is controlled by TGF-beta.
There are two different roles for TGF-Beta. The process of cell death is helped by it.
It's the amount that makes a difference. Cell division can be activated by a certain amount of TGF-beta. Apoptosis is caused by a lot of it.
Some people are not sure why people kill themselves. It is thought that it is an inherited trait from animals that lose fur in the hot summer months.
When a hair follicle dies, it doesn't kill its stem cells. When the stem cells receive a signal to regenerate, they divide, make new cells, and develop into a new follicle.
If scientists can determine more precisely the way TGF-beta stimulates cell division and how the chemical interacts with other genes, it could be possible to grow hair.
Many animals, including humans, have hair on their skin. One day, being able to more precisely control levels of TGF-beta could cure hair loss in millions of people.
Wang said that their work could offer something to help people.
More information: Katherine Dinh et al, A probabilistic Boolean model on hair follicle cell fate regulation by TGF-β, Biophysical Journal (2022). DOI: 10.1016/j.bpj.2022.05.035 Journal information: Biophysical Journal
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