Scientists have discovered a species ofbacteria that grows to the size and shape of a human eyelash.

Thousands of times bigger than Escherichia coli, these cells are the largestbacteria ever seen. Jean-Marie Volland said it would be like meeting another human the size of Mount Everest.

The study of Thiomargarita magnifica was published in the journal Science.

bacteria were thought to be too easy to make large cells Thiomargarita magnifica is quite complex. It's possible that even bigger, even more complexbacteria are waiting to be discovered with most of the world yet to be explored.

About 350 years ago, the Dutch lens grinder Antonie van Leeuwenhoek discovered the first case ofbacteria. He was amazed to see single-celled organisms in the dental plaque. Scientists discovered many more types ofbacteria that were invisible to the naked eye. The size of an E. coli cell is less than ten thousandth of an inch.

A pair of newbacteria can be formed from a single cell of thebacterial cell. bacteria cells live together The teeth of Van Leeuwenhoek were covered with a film ofbacteria. In lakes and rivers, somebacteria stick together to form small structures.

Our bodies are made up of 30 trillion cells. Our cells are larger than those ofbacteria, so they are not visible to the naked eye. A human egg cell can be up to five thousandths of an inch in size.

Cells from other species can grow to a foot long.

ImageA filament of Thiomargarita magnifica.
A filament of Thiomargarita magnifica.Credit...Jean-Marie Volland
A filament of Thiomargarita magnifica.
ImageThe bacteria was discovered in the mangroves of the Guadeloupe archipelago in the Caribbean.
The bacteria was discovered in the mangroves of the Guadeloupe archipelago in the Caribbean.Credit...Hugo Bret
The bacteria was discovered in the mangroves of the Guadeloupe archipelago in the Caribbean.

Scientists looked to evolution to understand the gulf between small and large cells. The animals, plants and fungi are all part of the same evolutionary line. Eukaryotes have many ways to build large cells. The scientists said that the cells had to stay small.

A big cell needs to be supported so that it doesn't fall apart. The poles in a tent are made of stiffmolecular wires. The cellular skeleton of the bacterium does not exist.

As the cell's volume increases, it takes longer for the molecule to drift around and find the right partners to carry out the chemical reactions.

This problem has been solved by filling cells with tiny compartments where different forms of biochemistry can occur. When a cell reproduces, they keep their DNA coiled up in a sac called the nucleus, along with molecule that can read genes to make a new copy of it. The cells generate fuel inside the pouch.

The compartments found in cells of the eukaryotes are not found inbacteria. Each bacterium carries a loop of its own genetic material around its interior. They do not have a source of energy. Instead of generating fuel with fuel cells, they usually use fuel with fuel cells. It works well for small cells. There isn't enough room on the surface of the cell for enough fuel-generating molecule as the cell volume increases.

The simplicity ofbacteria seems to explain why they are small.

Shailesh Date is the founder of the Laboratory for Research in Complex Systems and a co-author with Dr. Volland. After studying just a small portion of the world, scientists made a lot of generalizations aboutbacteria.

He said that they had just scratched the surface but that they had been very strict.

The dogma cracked in the 1990s. Somebacteria have their own compartments. The naked eye could see species that were visible. The Epulopiscium fishelsoni was discovered in 1993. The surgeonfish is home to 600 microns ofbacteria, which is the same size as a grain of salt.

The mangrove forests of Guadeloupe are a cluster of Caribbean islands that are part of France. The microbe looked like pieces of white spaghetti and formed a coat on dead tree leaves.

Dr. Gros wasn't sure what he had found. He thought the spaghetti could be something else. He and his colleagues found out they werebacteria when they took the samples from the lab.

Dr. Gros and Dr. Volland joined forces to study the strange organisms. They wanted to know if thebacteria were stuck together.

It wasn't the case. When the researchers looked at the noodles with microscopes, they realized they were their own cells.

Dr. Vallant and his colleagues haven't figured out how to grow the Thiomargarita magnifica in their lab. Each time the team wants to run a new experiment, Dr. Gros has to get a fresh supply ofbacteria. Oyster shells and plastic bottles can be found in the mangrove forest. The life cycle of the bacterium seems to be unpredictable.

Dr. Gros said he couldn't locate them in the last two months. I don't have a clue where they are.

ImageA sampling sites among the mangroves of the Guadeloupe archipelago. Lately, the bacteria have been hard to find there.
A sampling sites among the mangroves of the Guadeloupe archipelago. Lately, the bacteria have been hard to find there.Credit...Pierre Yves Pascal
A sampling sites among the mangroves of the Guadeloupe archipelago. Lately, the bacteria have been hard to find there.
ImageA giant cell of Thiomargarita magnifica reproduces by pinching off its tip into tiny new cells, each of which contains hundreds of compartments packed with DNA.
A giant cell of Thiomargarita magnifica reproduces by pinching off its tip into tiny new cells, each of which contains hundreds of compartments packed with DNA.Credit...Olivier Gros
A giant cell of Thiomargarita magnifica reproduces by pinching off its tip into tiny new cells, each of which contains hundreds of compartments packed with DNA.

Researchers have found a strange structure inside the cells of Thiomargarita magnifica. There are a lot of different types of compartments in their membranes. Thiomargarita magnifica may be able to grow to huge sizes thanks to these compartments.

The microbe can use the energy in nitrates and other chemicals in the mangrove to make fuel.

There are other compartments that look similar to human nuclei. The pepins, which the scientists call after the small seeds in fruit, contain a loop of DNA. Thiomargarita magnifica has hundreds of thousands of its own pepin, each of which has a single loop of its own genetic material.

Each pepin has factories for building things from its genetic material. Petra Levin is a microbiologist at Washington University in St. Louis who was not involved in the study.

It might be possible for Thiomargarita magnifica to create the extraProtein it needs. Each pepin is capable of making its own set of proteins.

Dr. Volland and his colleagues hope that they will be able to confirm the hypotheses after they grow thebacteria. How the bacterium are so tough without a skeleton will be tackled by them.

Dr. Volland said that you can remove a single filament from the water and put it in another vessel. How it holds together is one of the questions we haven't answered.

According to Dr. Date, there may be more giantbacteria waiting to be found.

We don't know how big they are. This bacterium has shown us how to get there.