Portugal and Spain drew in the Nations League opener in Seville, and it was the first appearance for Ricardo Horta in nearly eight years.
The first goal was scored by Spain's Alvaro Morata.
After coming off the bench, Horta tucked home Joao Cancelo's cross.
This fixture has not been won by either side in almost a decade.
Jordi Alba had a chance to win the game for Spain.
Spain's Carlos Soler and Portugal's Rafael Leao both had good chances to score, but failed to do so.
The visitors brought on a player in the second half, but he was not involved in the goal that tied the game at one point.
Spain have not won in nine games in the competition. The Nations League final was the other.
The Czech Republic defeated Switzerland in the other game.
The Czechs will host Spain and Portugal will host Switzerland.