EasyJet is to cancel more than 200 flights over the next 10 days, causing disruption for families on half-term holidays.
Between May and June, the airline said it would be cancelling about 24 flights a day from the airport.
To provide reliable services over this busy period, the cancellation was necessary.
airports across the UK were affected by the issue A further 20 Easyjet flights were canceled on Friday morning, with a small number of TUI flights also delayed.
The IT issue has been resolved and the latest cancellation is unrelated to that.
Air traffic control restrictions, runway works and airport handling delays are some of the issues that are impacting its operations.
The airline apologized for the late notice of some of the canceled flights, but said it was necessary to provide reliable services over the busy period.
Customers will be given the option to rebook their flight or receive a refund and can apply for compensation in line with regulations.
Friday is expected to be the busiest day since the start of the Pandemic, with around 8,000 flights expected to depart from UK airports over the weekend.
The RAC said drivers were planning an estimated 17.8 million leisure trips between Friday and Sunday. The day is expected to be busy.
Fans travelling to Paris for the final of the European soccer competition faced long delays at the Port of Dover.
Some supporters complained of chaos as they were stuck in long lines with holiday-makers heading abroad for half-term.
There were long waits at airports.
The easing of Covid restrictions on international travel has led to delays and cancelations at airports.
The travel industry cut thousands of jobs during the Pandemic, but has struggled to recruit staff, carry out security checks and train new workers as demand for flights has returned.