|Dates: 22 May-5 June Venue: Roland Garros, Paris|
|Coverage: Live text and radio commentaries of selected matches across BBC Radio 5 Live Sports Extra, the BBC Sport website and app|
Defending champion Novak Djokovic produced another outstanding display as he reached the French Open fourth round without dropping a set all week.
The Serbian man, who is 34 years old, won 6-3 6-3 6-2 and saved one break point in the third set.
The top seed is on course for a potential quarter-final meeting with Nadal.
On Friday, Nadal advanced to the last 16 with a win over Botic van de Zandschulp.
Felix Auger-Aliassime of Canada will face Nadal in Paris on Sunday.
An intriguing element to that match is that Auger-Aliassime's team is led by Nadal's uncle, who coached him to 16 of his 21 major titles.
Diego Schwartzman is the Argentine 15th seed and he is his last-16 opponent.
After a disrupted start to the year, Novak Djokovic is starting to look at his best and will face his biggest test so far this year when he faces Schwartzman in the second round of the French Open.
The Australian Open and the United States tournaments were not allowed for him because he was not protected against Covid-19.
He had only one tournament before the European clay-court swing and, after an understandably rusty start in Monte Carlo, reached the Madrid Open semi-finals before winning the Italian Open.
He showed why he is the favourite to win on the Paris clay with a superb performance against Bedene, which he made look routine.
The pressure was immediately put on the Slovenian's serve.
After saving five break points in his first two service games, a weak backhand into the net gave Bedene the advantage and he went on to win the match.
Bedene only got five receiving points for the first two sets, because of the way in which Djokovic served.
At the start of the third, the level of dominance dropped a bit, leaving the Serbian needing to fight off a break point in the opening game.
After breaking Bedene's serve for a 3-1 lead and then securing victory with a second break on his second match point, it was obvious that the Serbian was on his way to victory.
After missing two months of the season with a rib injury, Nadal is the fifth seed in Paris and will be looking for his 21st Grand Slam title.
The chronic foot problem that he thought would end his career last year flared up at the recent Italian Open.
He has not been overly worried by either his opponent or his body.
Nadal saw off a break point before serving out the win to set up a meeting with Auger-Aliassime.
The ninth seed Auger-Aliassime earned his spot in the last 16 with a win over Serbia's Krajinovic.
When Auger-Aliassime was linked to Nadal, he said he wouldn't be able to sit in his nephew's box.
Auger-Aliassime said that he believed that Toni would watch the match from a neutral place.
It was black and white from the first time we worked together, we knew it was a possibility that I would play Rafa.
John Isner was knocked out in five sets by Bernabe Zapata Miralles.
Although Isner fought back to take it to a decider, the world number 131 was able to reset and secure the victory, as he served for the match at 5-3 in the fourth set.
He will play either Alexander Zverev or Brandon Nakashima in the last 16.