The England squad will have two rookies in their ranks for next month's Nations League matches.
After scoring 18 goals and assisting another 13 in his first season at West Ham, and after returning from a serious knee injury, he is included for the first time.
He can play on either side of the defence and is likely to be useful in a squad with no left-backs.
Some players who were not in the most recent squad for the games against Hungary, Germany and Italy have been picked.
There are five right-backs in the squad.
Fikayo Tomori was recalled after winning the title with AC Milan, while Tammy Abraham was included after playing in the final of the Europa Conference League.
KalvinPhillips, John Stones, and other players were not in the wins over Switzerland andIvory Coast two months ago.
There is no place in the squad for Jordan Henderson, who has been playing regularly for the club and is preparing for the final against Real Madrid.
Emile Smith Rowe has also been left out. Shaw missed the end of the season with an injury and failed to make the squad.
Tyrick Mitchell and Kyle Walker-Peters did not retain their places after making their senior international debuts in March, while Fraser Forster was left out.
The two players who made their debut in March are retained.
The poor season of Manchester United has resulted in missing out on two players. It is the third squad in a row that Sancho has not been a part of, and the forward has not done enough to impress the manager, who admitted in March that he was not at his best.
There are no places for Eric Dier or James Maddison, desperate strong ends to the season.
There are no left-backs in the squad because Ben Chilwell has not been recalled.
Next month, England will play four Nations League games, starting with a trip to Hungary. The squad will travel to Germany on June 7 for a match, before playing Italy and Hungary at the same time.
Jordan Pickford, Nick Pope, and Aaron Ramsdale are the goalkeepers.
Goalkeepers: Trent Alexander-Arnold, John Stones, Fikayo Tomori, Kyle Walker, and Ben White.
James Ward-Prowse, Jude Bellingham, Mason Mount, Kalvin Phillips, and Declan Rice are in the middle.
The forwards are Tammy Abraham, Phil Foden, Jack Grealish, Harry Kane, and Bukayo Saka.