Thiago was injured on the final day of the season and is likely to be out for the final against Real Madrid.
The Reds fans were spurred on by Manchester City's struggles against Villa but were also determined to get a win over Wolves.
After Thiago set up Sadio Mane with a cute backheel in the first half, he appeared to pull a muscle and left the game.
I think he will be out of the final. He is limping, so it is not the best sign. He said that the lower part of the body was injured. I know what it is, but I don't want to say anything.
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Fabinho missed the FA Cup triumph on penalties after sustaining a muscle problem against Villa, and the club have doubts over his fitness.
Real Madrid won the title in the previous year in Kiev, but it was after Mohamed Salah was injured.
The Egyptian looked to have recovered from a knock in the win over Wolves by coming on and scoring their second goal to finish as the top scorer in the league.
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After seeing his team miss out on the title, he was disappointed but proud.
The boys played an incredible season, and the result ended their hopes of winning an unprecedented quadruple.
The whole journey of 21-22 so far is exceptional. The game showed how much these boys matter. The early goal gave us a knock. We did not play football like we usually do.
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We had to take off Thiago early, which is not helpful, but you still find a way. It is absolutely outstanding. We played 92 games and scored 92 points.
I am proud but I am disappointed. It is not cool but it is not completely unexpected. A lot of things have to happen.
The whole club of Man City and their coach,Pep Guardiola, are very happy. We were close but not close enough.
The date with Real in Paris must be quickly reset by the Reds, and they will try everything.
It has never been done before that you go completely without any knocks into a final. We had some knocks. The final has five days to be prepared. The team we face is very experienced. Losing the league increases the desire to put it right next week.