Virgil van Dijk and Mohamed Salah have been key players for Liverpool this season
The Reds will be without their top scorer and defender for Tuesday's crucial game against the Saints.
The pair went off during the FA Cup final at Wembley with injuries.
Both will return for the season finale against Wolves, according to the boss.
The target is they could be involved again at the weekend.
It is very positive. We are realistic about the Wolves game, but not tomorrow.
The Football News Show: Will fatigue be an issue for Liverpool in the title race with Man City?
The top scorer in the premier league is Salah with 22 goals.
Fabinho is out of Tuesday's game with a muscle injury while Andy Robertson is a doubt.
Manchester City leads the league by four points with a game in hand. Their title chances are over if they are defeated at St Mary's Stadium.
Both Fraser and Stuart are expected to be available for the visit of the Reds or the game against the Foxes.
Both had back and knee problems and only returned to training at the weekend.
MATCH FACTS
It's head-to-head.
Southampton have lost eight of the past nine league meetings, with the exception in that run being a 1-0 home victory in January 2021 courtesy of an early Danny Ings goal.
Saints can win a home league match against Liverpool in successive seasons for the first time since 2003-04 and 2004-05.
Liverpool defeated Southampton 4-0 at Anfield in the reverse fixture last November.
It's Southampton.
They need four points from their remaining two games to eclipse last season's final tally of 43.
Southampton have lost seven of their 10 most recent league matches, as many defeats as in their opening 26 fixtures of the season.
It's four losses in five home games for Ralph Hasenhuttl's side.
Only one of James Ward-Prowse's nine league goals this season has been scored at St. Mary's Stadium.
It'sLiverpool.
A Liverpool defeat would confirm Manchester City as Premier League champions.
The Reds have won 18 of 19 matches this season against teams currently in the bottom half of the table, only dropping points in a 3-3 draw at Brentford in September.
They have kept 21 Premier League clean sheets this season, a joint high alongside Manchester City and one short of equalling the club record set in 2005-06.
Liverpool could reach 10 top-flight away clean sheets in a campaign for the first time since 1984-85, when they ended with 11.
Pick your starting formation and line-up. You can either go for the team you want the boss to pick or the one you think he will choose.
Pick your starting line-up. You can either go for the team you want the boss to pick or the one you think he will choose.
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