The Commonwealth Games will be held in Bimingham, England, next year.
England defeated Jamaica 66-47 to win the three- match series.
The second game of the series was played at the Motorpoint Arena and the Roses took a 35-19 lead at the half-time break.
Jamaica was more competitive in the second half, but could not beat the hosts.
England beat Jamaica 55-45 in London last week.
Jess Thirlby, England's head coach, said he couldn't be happier with how they started.
It's another bit of history, since we haven't won a Test series against Jamaica in a long time.
The contest with Jamaica was postponed back in January because of travel restrictions between the two countries due to the coronaviruses.
The final match is on Sunday.
Quarter-time scores.
Q1 - 21-13
Q2 - 35-19
Q3 ended at 49-33.
Q4 - 66-47.
Starting seven.
England's goalkeepers are: G Francis,GD Guscoth,WD Cobden,C Guthrie,WA Haythornthwaite,GA Housby, GS Cardwell.
