Identifying small sites of disease initiation or characterizing the exact molecular changes that drive disease progression is difficult when working with animal models or post-mortem human organs.Bhatia et al. developed DISCO-MS, a 3D spatial-omics technology that uses robotics to obtain proteomics data from cells identified early in diseases. Image shows the aortic regions of a human heart whose vascular plaques are analyzed by DISCO-MS technology. Credit: Helmholtz Munich, Harsharan Singh Bhatia and Ali Ertürk
How can you find a damaged cell in an undamaged brain? There is a search looking for a needle. A new technology called DISCO-MS has been developed by the teams of Ali Ertrk at Helmholtz Munich and LMU Munich. DISCO-MS uses robotic technology to get data from sick cells.